Browsing Faculty Publications (CoM) by Author "Heialy, Saba Al"
Now showing items 1-9 of 9
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Asthma Associated Cytokines Regulate the Expression of SARS-CoV-2 Receptor ACE2 in the Lung Tissue of Asthmatic Patients
Heialy, Saba Al; Hachim, Mahmood Yaseen (2022)Abstract: It is still controversial whether chronic lung inflammation increases the risk for COVID-19. One of the risk factors for acquiring COVID-19 is the level of expression of SARS-CoV-2 entry receptors, ACE2 and ... -
Asthma severity as a contributing factor to cancer incidence: A cohort study
Hassan Khamis, Amar; Heialy, Saba Al (2021)Background: A putative link between asthma and asthma severity with the occurrence of cancer has been suggested but has not been fully investigated. The objective of this study is to assess the incidence of all types of ... -
Combination of obesity and co-morbidities leads to unfavorable outcomes in COVID-19 patients
Heialy, Saba Al; Hachim, Mahmood Yaseen (2020)Objective: Obesity has been described as a significant independent risk factors of COVID-19. We aimed to study the association between obesity, co-morbidities and clinical outcomes of COVID-19. Methods: Clinical ... -
Effect of bronchial thermoplasty on structural changes and inflammatory mediators in the airways of subjects with severe asthma
Heialy, Saba Al (2019-03-20)Background: Bronchial thermoplasty (BT) is a novel technique used in the treatment of subjects with severe refractory asthma. Radio frequency is provided to airway walls during bronchoscopy in order to reduce airway ... -
Interferon-Induced Transmembrane Protein (IFITM3) Is Upregulated Explicitly in SARS-CoV-2 Infected Lung Epithelial Cells
Hachim, Mahmood Yaseen; Heialy, Saba Al; Senok, Abiola C. (2020)Abstract: Current guidelines for COVID-19 management recommend the utilization of various repurposed drugs. Despite ongoing research toward the development of a vaccine against SARS-CoV-2, such a vaccine will not be available ... -
Leveraging the Added Value of Experiential Co-Curricular Programs to Humanize Medical Education
Senok, Abiola; John-Baptiste, Anne-Marie; Heialy, Saba Al; Naidoo, Nerissa; Otaki, Farah; Davis, Dave (2021)Background: The aftermath of the 1910 Flexner report resulted in significant gaps in the structure of medical education. Experiential co-curricular opportunities can contribute to addressing these gaps. Purpose: To ... -
Role of IL-17 in asthma pathogenesis and its implications for the clinic
Heialy, Saba Al (2019)Introduction: Asthma is a respiratory disorder typically characterized by T-helper type 2 (Th2) inflammation that is mediated by cytokines, including IL-4, IL-5 and IL-13. Pathophysiologically, airway inflammation involving ... -
Vitamin D Regulates the Expression of Glucocorticoid Receptors in Blood of Severe Asthmatic Patients
Heialy, Saba Al; Hachim, Mahmood Yaseen (2021)Purpose: Vitamin D (VitD) deficiency is a significant public health concern in many areas around the globe and has been associated with many immune-mediated diseases, including asthma. Severe asthma has been linked to a ... -
Vitamin D3 Attenuates Viral-Induced Inflammation and Fibrotic Responses in Bronchial Smooth Muscle Cells
Jalaleddine, Nour; Heialy, Saba Al (2021)Abstract: Toll-like receptor 3 (TLR3) activation by viral infections plays a key role in promoting inflammatory immune responses that contribute to pulmonary fibrosis in chronic inflammatory respiratory diseases. Vitamin ...